Quantity Price
1 - 5 $119.00
6 - 10 $114.00
11 - 20 $109.00
21+ $107.00
SKU: AM_618176100435 Categories: ,


Crespine Gel Plus

Buy Crespine Gel Plus to ease the pain of your patients who suffer from osteoarthritis. This product is a resorbable, viscoelastic, intraarticular solution that contains top-tier levels of pure hyaluronic acid. Osteoarthritis being the most common form of the chronic disease with many affected all over the world, this product is sure to be a boon for those who are looking for some way to ease the pain they constantly feel.

Which patients can benefit most from Crespine Gel Plus?

This product is intended for the use on patients who experience any pain or stiffness in their joints due to osteoarthritis. Specifically, this solution is indicated in correcting joints that have pathologically different synovial fluid, or have degenerated surface of the cartilage. After application of the solution, the patients will feel some level of relief from the pain, which will lead to a better quality of life.

Areas of Crespine Gel Plus focus 

There are two specific areas where the treatment is usually targeted, namely the knee joint and the hip joint. These are just two of the weight-bearing joints in the body, and it makes sense that these are the ones being targeted by Crespine Gel Plus.

How the treatment works

Swelling, stiffness, and general pain seem to be part and parcel of the lives of osteoarthritis patients, but BioPolymer did not want it to continue this way. Being a company specializing in the creation and production of medical devices, they started to formulate a solution to this ailment. What they came up with is Crespine Gel Plus, a single-injection treatment which can give patients quick-acting and long-lasting results. The hyaluronic acid (both cross-linked and non) base of the solution is very similar in terms of consistency to synovial fluid, and therefore is a viable solution to ensure that the bones stop rubbing against each other. The spaces between the bones are filled with this viscous and slippery formulation, ceasing the painful grinding of the bones. This solution also contains prilocainhydrochloride at 3.0mg which is capable of easing some of the discomfort caused by the injection itself. Aside from the aforementioned compounds, the product also contains sodium chloride and water for injection purposes.

Treatment details

Only licensed medical practitioners with pertinent training in experience in the injection of medical devices should apply this on patients. Anticoagulants like aspirin and ginkgo biloba should be avoided by the patient at least a few days prior to the injection. On the day of treatment, the affected joints should be thoroughly disinfected prior to injection. A needle with a suitable gauge should then be attached to the preloaded syringe and aspirated. In case blood is aspirated, needle reposition is advised to a suitable place. One prefilled syringe contains 2mL of the product, and is a sufficient amount for one treatment session.

How long will the treatment last?

The optimal level of pain relief achieved through the use of this product is generally reached at around 5 to 7 days post-injection. After this, the patients will be able to live a life free of osteoarthritis pain, swelling, or stiffness for six to eight months on average. After this period, or when the patients start to feel the effects of the disease again, they can get repeat treatments to extend the length of the effects as much as possible. Just like with any medical device though, cases vary wildly depending on physiology and lifestyle, so how long it really lasts will be different from patient to patient.

Safety information

The main compound of the formula is hyaluronic acid, which is a naturally-occurring substance in the body, meaning its injection is safe for patients. The product has also been CE marked, showing that it has passed multiple levels of safety certification to ensure most anyone can use it. However, people who are pregnant, breastfeeding, or are below the age of 18 are not targets for this product and therefore should avoid using this. Anybody with risk of hypersensitivity to any of the ingredients should also steer clear of this, and the doctor should avoid any areas where there are active inflammation or infection on the skin.

Other Side-effects

The common effects observed post-injection are mostly related to the injection process itself and include transient erythema, swelling, pain and tenderness, and a certain warming sensation in the joint. These are usually very mild and will mostly disappear within 5 days. Patients should be informed though that hypersensitive reactions can show themselves either instantly or even be as late as 2 to 4 weeks after treatment, and that they should constantly monitor their treated area.

Time needed for recovery

This product is not known to cause any downtime in patients and they are free to continue their normal day-to-day activities immediately after injection.

Cost of Crespine Gel Plus

The average cost per package of this product is around $113 per box. Each box contains one prefilled syringe and four traceability labels.

Bottom line

When it comes to providing fast-acting and long-term pain relief for osteoarthritis patients, this product is a good choice. Easy to administer and requiring only a single injection, BioPolymer has made sure to not only treat the pain from the disease, but also ensure the treatment itself is as comfortable and quick as possible. With hundreds of millions of people around the world suffering from at least one kind of arthritis, this product is sure to be a necessity for many.

Contact us now for any orders you might have, and we will guarantee safe and express delivery, as well as sure savings.